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Zydus Lifesciences vs Lupin: share price, P/E, ROE and financials compared

Prices as of 6 Nov 2026. Figures are from company filings and exchange data. This is an educational comparison, not investment advice.

Zydus Lifesciences

NSE: ZYDUSLIFE · Healthcare

₹1,197.90plus 0.41%

Lupin

NSE: LUPIN · Healthcare

₹1,988.10plus 0.01%

Zydus Lifesciences and Lupin at a glance

Zydus Lifesciences and Lupin are both listed in Healthcare. Zydus Lifesciences is the larger by market cap, at ₹1.2L Cr against ₹90,914 Cr for Lupin (1.3 times as large). On valuation, Lupin has the lower P/E (17.5× against 28.6×) and the lower price-to-book (3.78× against 4.29×). On returns and margins, Lupin has the higher ROCE (28.3% against 19.0%), the higher ROE (23.9% against 14.7%) and the higher operating margin (28.9% against 26.2%). Over three years, Lupin has faster 3-year sales growth (+19.1% against +16.5% a year) and faster 3-year profit growth (+131.4% against +37.0% a year). Lupin carries less debt for its equity, with a debt-to-equity of 0.26× against 0.46×.

Key metrics, side by side

Key metrics of Zydus Lifesciences and Lupin
MetricZydus LifesciencesZYDUSLIFELupinLUPIN
Price (₹)1,197.901,988.10
Market cap (₹ Cr)1,19,49190,914
P/E28.6×17.5× (the lower figure, shaded)
P/B4.29×3.78× (the lower figure, shaded)
Dividend yield, trailing0.08%0.91% (the higher figure, shaded)
ROE14.7%23.9% (the higher figure, shaded)
ROCE19.0%28.3% (the higher figure, shaded)
Operating margin (OPM)26.2%28.9% (the higher figure, shaded)
Net margin (NPM)13.8%16.9% (the higher figure, shaded)
Sales CAGR 3Y+16.5%+19.1% (the higher figure, shaded)
Profit CAGR 3Y+37.0%+131.4% (the higher figure, shaded)
Debt to equity0.46×0.26× (the lower figure, shaded)
Interest cover19.1× (the higher figure, shaded)17.7×
Net profit TTM (₹ Cr)–5,206
1Y return+22.8% (the higher figure, shaded)−0.5%
Promoter holding–46.84%

Shaded: the company with the more favourable reading (lower P/E, debt or P/B; higher ROE, ROCE, margins, growth or yield) when the gap is meaningful. n/m means not meaningful, for example ROCE for a bank. Loss-making companies’ multiples are shown but not ranked.

Zydus Lifesciences vs Lupin: common questions

Which is bigger, Zydus Lifesciences or Lupin?

By market cap, Zydus Lifesciences is bigger at ₹1.2L Cr, against ₹90,914 Cr for Lupin (prices as of 6 Nov 2026).

Which has a lower P/E ratio, Zydus Lifesciences or Lupin?

Zydus Lifesciences trades at a P/E of 28.6× and Lupin at 17.5×. Lupin has the lower P/E. P/E is the share price divided by earnings per share; it varies a lot between industries and with growth, so it says little on its own.

Which has a higher ROE, Zydus Lifesciences or Lupin?

Zydus Lifesciences reports a return on equity of 14.7% and Lupin 23.9%. Lupin has the higher ROE. ROE is net profit as a share of shareholders’ equity.

Which is growing faster, Zydus Lifesciences or Lupin?

Over the last three years: Sales grew +16.5% a year at Zydus Lifesciences and +19.1% at Lupin, so Lupin grew sales faster; profit grew +37.0% a year at Zydus Lifesciences and +131.4% at Lupin, so Lupin grew profit faster. Past growth doesn’t predict future growth.

Go to the stock pages for Zydus Lifesciences and Lupin, or add up to four more companies in the interactive comparison.